Clinical Evaluation of Platelet Rich Fibrin Versus Subepithelial Connective Tissue Graft for Soft Tissue Augmentation Around Implant in the Aesthetic Zone: A Randomized Control Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Crestal bone resorption
研究概览
简要总结
Soft tissue biotype is a critical factor for success of implant in the esthetic zone . Different soft tissue augmentation techniques have been employed to increase soft tissue thickness such as: autogenous grafts, allografts, xenografts and living cellular construct (LCC). Studies showed that, allografts and xenografts were inferior when compared with autogenous graft . However, few studies were conducted to evaluate the efficacy of soft tissue augmentation with platelet rich fibrin in order to overcome the patient morbidity with SCTG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with missing maxillary anterior toot teeth.
- •Thin gingival biotype.
- •Adequate inter-arch space for placement of the implant prosthetic part.
- •Good oral hygiene where gingival index is (0, 1) (Loe and Silness 1963).
排除标准
- •Patient with medical condition that is contraindicated with the surgical procedure
- •Patients receiving treatment that affect the healing ability.
- •Patients with local pathological defects related to the area of interest.
- •Smokers or pregnant women.
- •Patients with parafunctional habits that may jeopardize the implant longevity and affect the results of the study.
研究组 & 干预措施
sub epithelial connective tissue graft
The connective tissue graft will be harvested from the palate. Then the SCTG will be placed over the recipient site extending palataly and sutured.
干预措施: sub epithelial connective tissue graft (Procedure)
Platelet Rich Fibrin for soft tissue augmentation
blood will be drawn from the patient vein for PRF. The blood sample will be centrifuged for 10-12 min. PRF membrane is obtained
干预措施: Platelet Rich Fibrin (Procedure)
结局指标
主要结局
Crestal bone resorption
时间窗: 6 months
measured mesially and distally using periapical xray in mm
次要结局
未报告次要终点
研究者
may mohamed kamal
master student
Cairo University