NL-OMON34923
Withdrawn
Not Applicable
The effect of severe respiratory syncytial virus (RSV) lower respiratory tract infections in mechanically ventilated infants younger than 12 months of age on recurrent wheezing and lung function - RSV, mechanical ventilation and recurrent wheezing
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- bronchiolitis/pneumonia
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 70
- Status
- Withdrawn
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Age \< 12 months
- •\- Admitted with a first episode of RSV LRTD as defined with one or more of the following signs and symptoms: body temperature \* 37\.5° C, cough, rhinitis, wheezing on pulmonary auscultation, and crackles on pulmonary auscultation
- •\-Virogically confirmed RSV LRTD (i.e. a positive direct immunofluorescent assay (DIFA) or a positive RSV\-enzyme immunoassay (EIA)
Exclusion Criteria
- •\- Age \* 12 months
- •\- Infants born after a gestation \* 32 weeks
- •\- Infants with chronic lung disease of prematurity (defined by oxygen dependency between 28 and 56 days after birth)
- •\- Infants with a haemodynamically significant congenital heart disorder
- •\- Infants with an immunodeficiency
- •\- Infants with a congenital or acquired neuromuscular disorder
- •\- Infants managed only in the outpatient department
- •\- Infants with a nosocomial (i.e. hospital acquired) RSV LRTD
Outcomes
Primary Outcomes
Not specified
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