Can an extract of a patient's own blood prevent loss of tissue in the tooth socket after wisdom tooth extraction?

Not Applicable

Completed

• Conditions: Preservation of structure after upper third molar extraction; Oral Health

• Registration Number: ISRCTN34932978
• Lead Sponsor: niversidad Austral de Chile

Brief Summary

2021 Results article in https://doi.org/10.1016/j.joms.2020.10.006 (added 14/01/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-10-15
• Study Start: 2020-04-22
• Last Update Posted: 24 January 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

1. Men or women aged over 18 years
2. Indications for extraction of upper third molars for orthodontic treatment or difficult hygiene control at the Dental Clinic Center of the Universidad Austral de Chile (Valdivia, southern Chile)
3. Healthy, ASA I, without systemic diseases
4. Non-smoker
5. Oral hygiene index over 80% according to WHO criteria
6. Absence of caries or teeth in a radicular state
7. Participation approved through informed consent

Exclusion Criteria

1. Pregnant
2. Chronic periodontal disease
3. Chronic apical pathology
4. Receiving systemic or local pharmacological treatment in the last 3 months with antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs) or glucocorticoids
5. Acute infection of the tooth to be extracted
6. Receiving treatment with anticoagulants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Volume in mm3 of alveolar wound calculated from 3-dimensional images of plaster models obtained on both sides of the extracted third maxillary molars 7 days and 3 months after the extraction

Secondary Outcome Measures

Name	Time	Method
<br> 1. Mesiodistal dimension of alveolar wound, defined as the limit between keratinized gum (healthy tissue) and the presence of fibrin or blood clot, measured by a second investigator using a North Carolina periodontal probe (Hu-FriedyTM. Hu-Friedy Co. Frankfurt, Germany) at 7 days and 3 months post-extraction<br> 2. Vestibulopalatine dimension of alveolar wound, defined as the limit between keratinized gum (healthy tissue) and the presence of fibrin or blood clot, measured by a second investigator using a North Carolina periodontal probe (Hu-FriedyTM. Hu-Friedy Co. Frankfurt, Germany) at 7 days and 3 months post-extraction<br>