ISRCTN42986828已完成未知
Double blind placebo controlled trial of steroids in Bacterial Meningitis
niversity of Oxford (UK)0 个研究点目标入组 0 人开始时间: 2005年7月22日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
研究概览
简要总结
2004 Results article in https://pubmed.ncbi.nlm.nih.gov/15496623 2007 Results article in https://pubmed.ncbi.nlm.nih.gov/18077808
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. The treating physician believes the diagnosis to be BM
- •2. History less than ten days (unless still Serebrospinal Fluid [CSF] evidence of bacteria)
- •3. CSF white cell count more than 50 with more than 50% neutrophils
- •4. CSF glucose less than 50% of blood glucose
排除标准
- •1. Chest X-Ray (CXR) shows evidence of possible Tuberculosis (TB)
- •2. History is longer than ten days
- •3. History of hypersensitivity to beta-lactam antibiotics
- •4. Known severe liver or renal impairment
- •5. Patients in whom the physician believes corticosteroids are contraindicated e.g. uncontrolled diabetes, gastro-intestinal bleeding etc.
- •6. Pre-existing severe neurological disability
- •7. Pregnancy within the first trimester
研究者
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