Does Exclusive Consumption of Plant-based Dietary Protein Impair Resistance Training-induced Muscle Adaptations?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 2
- 主要终点
- Muscle strength
研究概览
简要总结
Dietary protein consumption maximizes the anabolic response during resistance training (RT) by triggering muscle protein synthesis and providing the indispensable amino acids for a net positive protein balance. Leucine is considered the key amino acid in this process, suggesting that differences in protein quality may influence RT-induced gains in muscle mass and strength. In general, plant-based protein sources have lower leucine concentrations than animal-based protein sources and human skeletal muscle. In this respect, despite acute evidence on lower anabolic properties of plant- vs. animal-based protein, the effects of an exclusive plant-based dietary protein diet on RT-induced adaptations are currently unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy young men
- •Vegans ≥ 1 y or omnivorous subjects
- •Physically active but no resistance-trained subjects
- •Without any chronic injury that impairs resistance training performance
- •Protein intake > 0.8 g/protein/kg body weight
排除标准
- •Use of creatine or beta-alanine supplements for the last 3 months
- •Use of proteins and/or amino acids supplements for the last 1 month
- •Engagement in specific dietary restrictions
- •Previous use of anabolic steroids
- •Engagement in any training program
研究组 & 干预措施
Omnivorous
Interventions: Daily protein intake was adjusted to 1.6g/kg/day via supplementation (whey) + 12 weeks of resistance training
干预措施: whey protein (Dietary Supplement)
Vegan
Interventions: Daily protein intake was adjusted to 1.6g/kg/day via supplementation (soy) + 12 weeks of resistance training
干预措施: soy protein (Dietary Supplement)
结局指标
主要结局
Muscle strength
时间窗: 12 weeks
assessed by leg-press one-maximum-repetition
Muscle cross-sectional area
时间窗: 12 weeks
assessed by mode-B ultrasound
次要结局
- Leg lean mass(12 weeks)
- fiber cross-sectional area(12 weeks)
研究者
Bruno Gualano
Professor
University of Sao Paulo