Manipulation of Dietary Protein and the Anabolic Response
Not Applicable
Completed
- Conditions
- Focus: Anabolic Response to Food Intake in Young IndividualsCondition Relevance: Skeletal Muscle Health, Sarcopenia
- Interventions
- Dietary Supplement: High protein intakeOther: Placebo comparator
- Registration Number
- NCT01820975
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 28
Inclusion Criteria
- Males
- Aged between 18-35 years
- Healthy, recreationally active
- BMI < 30 kg/m2
Exclusion Criteria
- Smoking
- Allergies to milk proteins (whey or casein)
- Vegetarians
- Diagnosed GI tract diseases
- Female
- Arthritic conditions
- A history of neuromuscular problems
- Previous participation in amino acid tracer studies
- Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High protein intake High protein intake High protein intake: large bolus of protein in teh diet the day before testing No protein intake Placebo comparator No protein in the diet the day before testing
- Primary Outcome Measures
Name Time Method Muscle protein fractional synthetic rate following protein ingestion 3 hours The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.
- Secondary Outcome Measures
Name Time Method