Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss

Not Applicable

Completed

• Conditions: Mood; Appetite; Weight Loss
• Interventions: Other: Beef/Pork; Other: Soy/Legumes

• Registration Number: NCT01005563
• Lead Sponsor: Purdue University

Brief Summary

The primary aims of this study are to assess the effects of habitual dietary protein intakes across the acceptable macronutrient distribution range with lean beef/pork or soy/legumes as the predominate sources of protein on indices of daily appetite and mood, and on postprandial appetite, mood, energy expenditure, and glycemic responses during energy-restricted weight loss in overweight adults.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-10-30
• Study First Submitted QC: 2009-10-30
• Study First Posted: 2009-11-01
• Study Start: 2010-01
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2014-03
• Last Update Submitted: 2014-03-19
• Last Update Posted: 2014-03-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Age range: 21 years and older
• Body mass index between 27.0-36.9 kg/m2
• Non-smoking (within the last 6 months)
• Weight stable (< 3 kg (~7 lbs) weight gain or loss within last 3 months)
• Energy need for weight maintenance 1950-2750 kcal/day
• Not dietary restrained
• Menstruating women not pregnant or lactating
• Constant habitual activity patterns (within last 3 months)
• No Acute Illness (or have chronic diseases known to influence protein or energy metabolism)
• Non-diabetic
• Clinically normal blood profiles (within 10% of clinical normalcy)
• Non-hypertensive
• Not taking medications known to influence appetite or metabolism
• Willingness to eat study foods
• Able to travel to testing facility

Exclusion Criteria

• Age: <21 years
• Body mass index: outside of the 27.0-36.9 kg/m2 range
• Smoker (currently or within the last 6 months)
• Gained or lost > 3.0 kg (7 lbs) within the last 3 months
• Energy need for weight maintenance < 1950 or > 2750 kcal/day
• Dietary restrained (≥ 14 on Three Factor Eating Questionnaire)
• Pregnant, lactating, or non-menstruating women
• Clinically diagnosed as a diabetic, or with liver or kidney disease/dysfunction, or osteoporosis
• Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
• Hypertensive
• Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
• Allergies to eggs
• Lactose intolerance
• Unwillingness to eat study foods
• Inability to travel to testing facility

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Arm 1: Beef/Pork	Beef/Pork	Participants consuming diet with beef/pork as predominate sources of protein
Arm 2: Soy/Legumes	Soy/Legumes	Participants consuming diet with soy/legumes as predominate sources of protein

Primary Outcome Measures

Name	Time	Method
Increasing protein intake from lean beef/pork or soy/legumes sources will result in progressively decreased daily composite hunger and desire to eat, and increased fullness. The responses will not be different between groups of subjects.	14 weeks

Secondary Outcome Measures

Name	Time	Method
Increasing the protein content of a test will result in progressively more robust and sustained changes in postprandial appetite and energy expenditure and blunted glycemic response. The responses will not be different between the groups of participants.	14 weeks

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States