NCT00262353撤回不适用
Elimination of Protein-bound Uremic Retention Solutes by Prometheus Artificial Hepatic System Versus Conventional Dialysis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Determination of the concentration of protein-bound toxins after treatment with different artificial devices
研究概览
简要总结
Comparison of the efficacy of dialysis by conventional dialysis versus Prometheus artificial hepatic system
详细描述
After inclusion, patients will be dialysed with low-flux artificial kidneys. 1 week of dialysis exists of 3 days of dialysis. In week 4, day 2, patients will be treated once with the Prometheus artificial hepatic system or with high-flux dialysis. The other days low-flux kidneys will be used. Week 5 and 6 are a wash-out period. Week 7 is identical to week 4 but the other system than in week 4 is used. Blood samples are taken at regular moments in week 3, week 4 (day 2) and week 7 (day 2).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stable patients
- •At least 3 months on dialysis
- •Arterio-venous fistula
排除标准
- •Diabetic patients
- •Malignancies
- •Acute illnesses
结局指标
主要结局
Determination of the concentration of protein-bound toxins after treatment with different artificial devices
次要结局
- Determination of the kinetics of protein-bound toxins after treatment with different artificial devices
研究者
研究点 (2)
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