ACTRN12619000204145已完成未知
A randomised controlled trial examining the effect of blood and plasma donation on serum per- and poly-fluoroalkyl substances (PFAS) levels in Metropolitan Fire Brigade staff
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 285
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 70 Years（—）
- 性别
- All
入选标准
- •1. Metropolitan Fire Brigade staff with 10 or more years of previous occupational exposure to PFAS.
- •2. PFOS levels >=5ng/mL
- •3. Eligible to donate blood (in accordance with the ARCBS guidelines).
- •4. Not donated blood in the past 3 months.
- •5. Signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the trial prior to enrolment.
- •6. Willingness and ability to comply with scheduled visits, laboratory tests and other study procedures.
排除标准
- •1. Medical contraindication to blood donation.
- •2. Other severe acute or chronic medical or psychiatric condition, or laboratory abnormality that may increase the risk associated with study participation or study drug administration or may interfere with the interpretation of study results, and in the judgment of the investigator would make the participant inappropriate for entry into this study.
- •3. Previous ineligibility to donate blood.
- •4. Planned travel or extended leave (e.g. >6 weeks) that would prevent access to blood donation facilities.
研究者
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