Quantification of muscular fatty degeneration in brachial plexus injury patients

Completed

• Conditions: Brachial plexus injury; injury of the nerves innervating the arm; 10029317

• Registration Number: NL-OMON35089
• Lead Sponsor: Orthopaedie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

Brachial plexus injury diagnosed by orthopaedic surgeon or neurosurgeon.
Patiënts have to be in end stage of neural regeneration i.e. at least 2 years after trauma or nerve surgery

Exclusion Criteria

Bilateral brachial plexus injury.
Not 3 tesla MRI eligible due to any reason.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameters are:<br /><br>1) the percentage of muscular fat in the musculus biceps brachii and triceps<br /><br>of the affected and contralateral arm.<br /><br>2) The Goutallier grading will be used to compare qualitatively grading method<br /><br>with the quantifative grading method of muscular fat content.<br /><br>The m. biceps brachii and triceps of the contralateral non affected arm will be<br /><br>used as a control muscles. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are:<br /><br>1) elbow flexion and extension range of motion and strength<br /><br>2) quality of life questionnaire: SF36 and DASH</p><br>