Aqueous olanexidine versus alcohol-based chlorhexidine for surgical skin antisepsis on the incidence of surgical site infections

Not Applicable

Recruiting

• Conditions: Surgical site infection

• Registration Number: JPRN-UMIN000049712
• Lead Sponsor: Keio University School

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-12-07
• Last Update Posted: 17 October 2023
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 700

Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients with a history of allergy to alcohol, including oranexidine gluconate or chlorhexidine gluconate alcohol 2) Patients who cannot be followed up for 30 days after surgery 3) Patients with active infection (except viral hepatitis) 4) Patients who have received antimicrobial agents the day before surgery 5) Emergency surgery and surgery requiring disinfection of mucous membrane surfaces and wound sites 6) Patients with a history of asthma 7) Other patients deemed by the physician to be unsuitable for the safe conduct of this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative 30-day surgical site infection rate

Secondary Outcome Measures

Name	Time	Method
postoperative 30-day superficial incisional SSI rate, deep incisional SSI rate, organ/space SSI rate, positive bacterial wound culture rate, bacterial strain, intervention-related toxicity and allergic events rates, reoperation rate due to SSI, medical economic effect indicator, hospitalization duration.