Evaluation of toothpaste containing novel antimicrobial agent for controlling plaque and gum diseases

Phase 1

• Registration Number: CTRI/2020/01/023024
• Lead Sponsor: Salicylates and chemicals pvt ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Subjects between the ages 18 and 50(inclusive);and in generally good health.

2.Subjects who are available for the entire study period .

3.Subjects had to possess atleast 20 uncovered permanent natural teeth (excluding thrid molars)

4.Mean plaque index score of atleast 1.5 determined by the turesky modification of the Quigley -Hein plaque index will be enrolled in the study.

5. mean gingival index score of 1 determined by modified loe and sillness index

Exclusion Criteria

If they had advanced periodontal disease (purulent exudate,tooth mobility, and /or extensive loss of periodontal attachment or alveolar bone.

2. Five or more decayed carious lesions requiring immediate restorative treatment.

3.Tumor(s) of the soft or hard oral tissues of oral cavity ,or presence of partial removable dentures or presence of orthodontic bands

4.Subjects on any prescribed medications that could interfere with the study outcome or used antibiotics within 1 month prior to the study

5. If they started taking then during the course of the study or received a dental prophylaxis in the 2 weeks prior to the baseline examination .

6.Pregnant or lactating women ,individuals who are participating in any other clinical study ,or individuals who had participated in a study , or individuals with history of alcohol or drug abuse were not allowed to participate in the study

7. Subjects with the history of allergies to the taste products , or allergies to oralcare , / personal care consumer products or their ingredients ,or subjects with existing medical conditions which prohibits them from eating and drinking for periods up to 4 hours were also excluded from the study .

Study & Design

• Study Type: Interventional
• Study Design: Not specified