NL-OMON44156已完成不适用
The effect of periodontitis on innate immune activation and vascular wall inflammation in relation with atherosclerosis - PERIO-IIM
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Age between 40 and 80 years
- •- With or without severe periodontitis with DPSI score of 0-2 resp. 4
- •- Written informed consent
排除标准
- •- Cardiovascular events
- •- Diabetes mellitus
- •- Chronic infections other than periodontitis
- •- Medical history of any disease associated with immune deficiency (either congenital or acquired, including chemotherapy, chronic steroid use, organ transplant)
- •- Fever (T > 38.5) or antibiotics use for infectious disease within 1 month prior study entry
- •- Chronic use of anti-inflammatory drugs such as NSAIDs
- •- Recent hospital admission or surgery with general anaesthesia (< 3 months)
- •- Known heart failure, chronic kidney (MDRD <45 ml/min) or liver disease (ALAT more than three times upper reference limit or known liver disease)
- •- Inability to personally provide written informed consent (e.g. for linguistic or mental reasons)
- •- Inability to undergo PET-CT scanning, including pregnancy
研究者
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