Secondary macular edema after Descemet*s Stripping Automated Endothelial Keratoplasty (DSAEK): a prospective, non-comparative study.

Completed

• Conditions: macular edema; 10047060

• Registration Number: NL-OMON32110
• Lead Sponsor: Oogziekenhuis Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- age >= 18 years of age
- informed consent
- Fuchs* endothelial dystrophy or Pseudophakic Bullous Keratopathy requiring DSAEK
- cornea that allows preoperative OCT imaging
- pseudophakic

Exclusion Criteria

- previous ocular surgery that could influence visual outcome
(except uneventful cataract surgery)
- other macular or inflammatory disease that could influence the incidence of CME
(eg. diabetic retinopathy, diabetic maculopathy, retinal vein occlusion, uveitis)
- ocular disease that could influence visual outcome
(except Fuchs`endothelial dystrophy or PBK)
- other ocular surgery planned within 12 months following inclusion in this study
- systemic therapy that could influence the occurrence of macular edema
(eg. Avandia, Acetazolamide)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Incidence of CME at 1, 3 and 6 months after DSAEK.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Relationship risk factors and pre-op macular condition with post-op CME.</p><br>