To assess levels of stress, serum and salivary Ghrelin and Cortisol in Stage III Periodontitis with smokers and non- smokersâ?? A Cross-sectional Study.
Not Applicable
- Registration Number
- CTRI/2019/06/019542
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Group I: Periodontally healthy subjects with no signs of periodontal disease and smoking.
Group II: Current Smokers with untreated stage III periodontitis, PPD >= 6 mm and CAL >= 5mm.
Group III: Non-smokers with untreated stage III periodontitis, PPD >= 6mm and CAL >= 5mm.
Exclusion Criteria
1. Patients with self-reported psychiatric disorders or on anti-psychotic medications.
2. Patients with any systemic disease.
3. Pregnant and post-menopausal women.
4. Patients with history of antibiotic intake within 6 weeks.
5. Patients undergoing corticosteroids or immune-suppressive therapy.
6. Patients with symptoms of acute illness.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the stress, serum and salivary cortisol and ghrelin levels in smokers and non-smokers with stage III periodontitis.Timepoint: 18 months
- Secondary Outcome Measures
Name Time Method To evaluate and compare the serum and salivary ghrelin and cortisol levels in periodontally healthy patients, smokers and non-smokers with stage III periodontitis.Timepoint: 18 months