To assess whether providing Kenya?s first line anti-malarial treatment in shops at a subsidised price can increase the share of young children who receive appropriate treatment for malaria

Completed

Conditions: Malaria
Infections and Infestations
Unspecified malaria

Registration Number: ISRCTN59275137

Lead Sponsor: Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Programme (Kenya)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 1161

Inclusion Criteria

Added as of 27/01/2009:
Please note that the specified minimum amount of time for which the selected retail outlets should have been functioning has been identified as a minimum period of six months prior to the baseline survey.

Initial information at time of registration:
1. All children under five years of age (either sex) from whom care is sought for fever from participating retail shops serving the population in the intervention sub-locations
2. Selected retail outlets either within or serving the intervention sub-locations which are perceived to be well established, respected businesses by the local community, who stock anti-malarials or anti-pyretics and have been functioning for a specified minimum amount of time (time of functioning to be determined following baseline retail census)

Exclusion Criteria

Current information as of 16/04/2010:
1. Children less than 3 months. These children will be referred directly to a health facility.
2. Children 3 - 59 months, suffering from Integrated Management of Childhood Illness (IMCI) danger signs. These children will be referred directly to a health facility.
3. Retail shops serving the intervention sub-locations that do not sell anti-pyretics or anti-malarials, have been functioning for less than the specified amount of time defined from the baseline retail census, and are not perceived to be well established, respected businesses by the local community

Initial information at time of registration:
1. Children under 5 kg suffering from Integrated Management of Childhood Illness (IMCI) danger signs. These children will be referred directly to a health facility.
2. Retail shops serving the intervention sub-locations that do not sell anti-pyretics or anti-malarials, have been functioning for less than the specified amount of time defined from the baseline retail census, and are not perceived to be well established, respected businesses by the local community

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the impact on the proportion of children under five with fever being treated promptly with appropriate anti-malarial treatment, and adhering to the correct dose. <br><br>Timepoints for both primary and secondary outcomes: <br>At baseline, through household and provider surveys conducted over a four month period prior to the intervention. At follow-up, through household and provider surveys conducted over a three month period, nine to twelve months after the start of the intervention.

Secondary Outcome Measures

Name	Time	Method
1. To determine if private sector retailers can deliver AL to appropriate standards of quality for the treatment of fever in children under five years (provision)<br>2. To determine distribution of benefits of retail sector delivery of AL by socio-economic status (equitable coverage)<br>3. To explore reasons for the impact observed and identify any challenges in the implementation process <br><br>Timepoints for both primary and secondary outcomes: <br>At baseline, through household and provider surveys conducted over a four month period prior to the intervention. At follow-up, through household and provider surveys conducted over a three month period, nine to twelve months after the start of the intervention.