Skip to main content
Clinical Trials/NCT01658072
NCT01658072
Completed
Not Applicable

Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia

Hospital for Special Surgery, New York1 site in 1 country90 target enrollmentFebruary 2012
ConditionsOsteoarthritis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoarthritis
Sponsor
Hospital for Special Surgery, New York
Enrollment
90
Locations
1
Primary Endpoint
Time Until Patient is Ready for Discharge
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The best way to provide analgesia after total hip arthroplasty is hotly debated. There are two protocols in use at Hospital for Special Surgery(HSS). Both protocols have their proponents, but there are limited data for making an informed choice of protocols. For total hip arthroplasty at HSS, epidural analgesia is used most frequently as it reduces pain with physical therapy. However, epidural analgesia can be associated with nausea, pruritis, dizziness, and orthostatic hypotension. These side-effects can slow physical therapy and may prolong the time until the patient is ready for discharge. Some surgeons at HSS have decided to use a different analgesic protocol, based on a peri-articular injection. This protocol avoids epidural analgesia and systemic opioids. However, patients are given oral opioids as part of a multimodal pain therapy. The investigators propose to compare peri-articular injection to epidural patient controlled analgesia (Epidural PCA). The investigators will enroll 90 total patients (45 per study arm). The enrollment period will be approximately one year and the duration of the follow-up with study patients will be three months following their procedure.

Registry
clinicaltrials.gov
Start Date
February 2012
End Date
May 2013
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hospital for Special Surgery, New York
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with osteoarthritis scheduled for primary total hip arthroplasty with a participating surgeon
  • Age 50 to 80 years old
  • Planned use of regional anesthesia
  • Ability to follow study protocol

Exclusion Criteria

  • Patients younger than 50 years old and older than 80
  • Patients intending to receive general anesthesia
  • Allergy or intolerance to one of the study medications
  • Patients with an ASA of IV
  • Patients with insulin-dependent diabetes
  • Patients with hepatic (liver) failure
  • Patients with chronic renal (kidney) failure
  • Chronic opioid use (taking opioids for longer than 3 months)
  • Patients with any prior major ipsilateral hip surgery
  • Allergy to any of the medications (or adhesives) involved in the protocol

Outcomes

Primary Outcomes

Time Until Patient is Ready for Discharge

Time Frame: Length of Hospital Stay, an expected average of 3 days

"readiness for discharge" to home or to a rehabilitation facility (compared to the HSS standard regimen of epidural analgesia) after total hip arthroplasty.

Study Sites (1)

Loading locations...

Similar Trials