Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion in Combination With Patient Controlled Analgesia: a Prospective Randomized, Double-blinded, Placebo-controlled Study
Overview
- Phase
- Phase 1
- Intervention
- Normal Saline
- Conditions
- Postoperative Pain Management After Total Hip Arthroplasty
- Sponsor
- Loma Linda University
- Primary Endpoint
- We propose to test the hypothesis that adding a low dose lidocaine infusion to patient controlled analgesia will lower the amount of opioids that these patients will receive, thereby improving patient safety while still providing adequate analgesia.
- Status
- Withdrawn
- Last Updated
- 11 years ago
Overview
Brief Summary
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center & East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to the patient controlled analgesia pump. These groups will be compared to one another statistically to determine which group shows the safest and most satisfying pain control.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult male or female undergoing a total hip arthroplasty Subject is American Society of Anesthesiologists physical status 1, 2, or 3 Subject has voluntarily signed and dated the informed consent document approved by the IRB Be English speaking
Exclusion Criteria
- •Age \> 80 years old or younger than 18 years old Congestive heart failure Hepatic insufficiency Neurological disorders Psychiatric disorders Steroid treatment No history of atrial fibrillation Chronic pain disorder with opioid treatment
Arms & Interventions
Control Group
Patients will receive a Dilaudid PCA in combination with a placebo infusion of normal saline.
Intervention: Normal Saline
Lidocaine Group
Patients will be receive a Dilaudid PCA in combination with a continuous Lidocaine infusion.
Intervention: Lidocaine
Outcomes
Primary Outcomes
We propose to test the hypothesis that adding a low dose lidocaine infusion to patient controlled analgesia will lower the amount of opioids that these patients will receive, thereby improving patient safety while still providing adequate analgesia.
Time Frame: 24 hours