Management of Postoperative Pain After Total Hip Arthroplasty
Overview
- Phase
- Phase 2
- Intervention
- Bupivacaine
- Conditions
- Osteoarthritis of Hip
- Sponsor
- Chang Gung Memorial Hospital
- Locations
- 1
- Primary Endpoint
- Pain VAS score
- Last Updated
- 16 years ago
Overview
Brief Summary
Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and vascular exposure. Post-operative pain after such surgery is exacerbated on movement or by reflex spasms of the muscles, which may delay mobilization, reduce satisfaction, prolong hospitalization, and possibly increase medical costs.
We design a prospective randomized study for postoperative pain control following total hip arthroplasty.
Investigators
Eligibility Criteria
Inclusion Criteria
- •diagnosed for surgery of osteoarthritis of hip
- •ability to tolerate surgery under general anesthesia.
Exclusion Criteria
- •refusal or the lack of mental ability to provide informed consent
- •neuropathic pain or sensory disorders in the leg requiring surgery
- •previous surgery of the hip joint
- •coagulation abnormalities
- •severe renal or hepatic impairment
- •chronic opioid users
- •known history of intolerance to the drugs used in the study
Arms & Interventions
Experiment
Anesthetics intraarticular injection
Intervention: Bupivacaine
Placebo
saline intraarticular injection
Intervention: Placebo
Outcomes
Primary Outcomes
Pain VAS score
Time Frame: pre-operaton, immediately post operation, postop 6hrs, postop 12hrs, postop 18hrs, postop 24hrs, post op 48hrs, postop 72hrs
Secondary Outcomes
- Functional score: WOMAC hip score, SF-36(Pre-operation, immediately post-operation, postop 6 weeks, postop 12 weeks)