Prolonged Sitting on Responses to Short-Term Exercise Training

Not Applicable

Completed

• Conditions: Metabolic Syndrome; Atherosclerosis
• Interventions: Behavioral: Active walking with exercise.; Behavioral: Prolonged sitting with exercise

• Registration Number: NCT03352063
• Lead Sponsor: University of Texas at Austin

Brief Summary

Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-09
• Study First Submitted QC: 2017-11-21
• Study First Posted: 2017-11-24
• Study Start: 2018-07-17
• Primary Completion: 2020-04-30
• Study Completion: 2020-05-30
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-29
• Last Update Posted: 2021-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• 18 to 35 years

Exclusion Criteria

• cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
• respiratory problems
• musculoskeletal problems that prevent prolonged sitting or exercise
• obesity
• susceptibility to fainting
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Walking with exercise	Active walking with exercise.	Subjects will complete a short term training protocol while sitting \<5 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.
Sitting with Exercise	Prolonged sitting with exercise	Subjects will complete a short term training protocol while sitting \>11 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.

Primary Outcome Measures

Name	Time	Method
Plasma Triglycerides	6 hours	Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test

Secondary Outcome Measures

Name	Time	Method
Plasma Insulin	6 hours	Areas under the curve for insulin concentration will be calculated for hourly samples from a 6-hour lipid tolerance test
Plasma glucose	6 hours	Areas under the curve for glucose concentration will be calculated for hourly samples from a 6-hour lipid tolerance test

Trial Locations

Locations (1)

University of Texas at Austin Human Performance Laboratory; 🇺🇸 Austin, Texas, United States