A comparative study of the effect of addition of morphine to ropivacaine and ropivacaine alone for preemptive transverse abdominis plane block on the perioperative analgesia on patients undergoing laparoscopic cholecystectomy -a randomized control trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Visual analogue score
研究概览
简要总结
A comparative study of the effect of addition of morphine to ropivacaine and ropivacaine alone for preemptive transverse abdominis plane block on the peri operative analgesia on patients undergoing laparoscopic cholecystectomy is a double blinded randomized control trial
The primary outcome to assess analgesic efficacy with respect to VAS score and the secondary outcome to assess the intraoperative total opioid consumption and to assess intraoperative hemodynamic changes and to assess time for the first rescue analgesia and total number of doses of rescue analgesia in 24 hours
Study will be conducted in Bangalore medical college attached hospitals with sample size of 40
Duration of study is from July 2025 to December 2026
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who are willing to give informed consent ASA grade 1 Patients with BMI 18.5-25 Patients undergoing laparoscopic cholecystectomy surgeries lasting less than 4 hours.
排除标准
- •Patients refusal Patients with history of coagulopathy Patients with history of allergic to local anaesthetic Patients with severe systemic disease Psychiatric illness Chronic medication taking for pain Patients requiring postoperative mechanical ventilation Localized infection over injection point Technical failure.
结局指标
主要结局
Visual analogue score
时间窗: 24 hours
次要结局
- To assess the time to first rescue analgesia & number of doses of rescue analgesia(24 hours)
研究者
Dr Aravindu
Bangalore Medical College and Research Institute