Clinical Efficacy of External Counterpulse Therapy and the effect on Vascular Endothelial Function in Patients with Primary Hypertension: an explorative randomized, double blinded, controlled pilot st

Not Applicable

• Conditions: Primary Hypertension

• Registration Number: ITMCTR2100005354
• Lead Sponsor: Ruian hospiytal of traditional Chinese medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Age 35-80 (including 35 and 80), gender is not limited
2. According to the Chinese Guidelines for the Prevention of Hypertension (Revised 2018),Patients diagnosed with primary hypertension levels 1-2
3. Understand and sign informed consent form

Note: The above three items must be met at the same time before they can be included in the study.

Exclusion Criteria

1. In contraindications of anti-pulse therapy :Hypertension grade 2 or higher; severe heart failure, 1 month history of heart infarction, severe aortic valve insufficiency, atrial fibrillation and frequent ventricular velocity.
2. Take medication that affects blood pressure fluctuations: e.g. have been taking birth control pills for less than three months.
3. Secondary hypertension: renal parenchyma and renal vascular hypertension, endocrine hypertension, aortic constriction, obstructive sleep apnea hypoventilation syndrome, pharmacogenic hypertension (including female contraceptives, eugene, partial diet pills, left dopa, non-dixie drugs, glucocorticoids, partial immunosuppressants, erythropoietin, etc.).
4. Unable or unwilling to comply with the study plan

Note: any items that meet the requirements should be excluded.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
vascular endothelial growth factor indicators;24 Hour Ambulatory Blood Pressure Monitoring;The change of mean SBP and DBP at the end of interventiona compares to the baseline.;

Secondary Outcome Measures

Name	Time	Method
Serum Biochemical Indicators;carotid-femoral pulse wave velocity;