Influence of Covid-19 related olfactory dysfunction on the development of quality of life

Recruiting

Conditions: Covid-19 related olfactory dysfunction

Registration Number: DRKS00030570

Lead Sponsor: Klinik und Poliklinik für Psychotherapie und Psychosomatik

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 306

Inclusion Criteria

Gender: both, male and female;
Minimum Age: 18 years;
Covid-19-related olfactory loss

Exclusion Criteria

Significant other health impairments (e.g., diabetes mellitus, renal insufficiency) that may be associated with disorders of olfactory function;
Acute or pronounced chronic inflammation of the nose and paranasal sinuses;
Additional relevant pre-existing or concomitant diseases in the ENT area, or with underlying brain-organic diseases;
Current pregnancy

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Influence of covid-19-related olfactory loss on psychological well-being and general life satisfaction, as well as olfactory loss-related changes in sexuality and relationship quality within committed partnerships and influence on relationship quality of patients with their biological children. As primary outcome, we are interested in general life satisfaction as well as mental health (assessed with WHO Wellbeing Index; PHQ-4, Löwe et al., 2010; BDI-II, Hautzinger et al., 2010), relationship quality in partnership (Partnership Satisfaction Questionnaire; Kliem et al., 2012) and in parent-child relationship (PBQ, Brockington et al., 2006). These parameters are collected at all 5 measurement time points by means of questionnaires. <br><br>

Secondary Outcome Measures

Name	Time	Method
Perception of body odors within the partnership and parent-child relationship (Pleasantness, Intensity, Identification). In an additional experiment after T2 for N = 50 participants, body odors of the partner (N=25) and of the own child (N=25) will be evaluated in comparison to age- and sex-matched body odors of healthy control subjects. The following outcomes will be collected: Identification of body odor (partner/child vs. unknown body odor); pleasantness rating, intensity rating of odor.