Olfactory Training Effects On Post-Covid-19 Hyposmia
Phase 2
Recruiting
- Conditions
- Coronavirus as a cause of diseases classified in other chaptersC10 Doenças do Sistema Nervoso
- Registration Number
- RBR-10wqyg2r
- Lead Sponsor
- Hospital Universitário Professor Edgard Santos- Universidade Federal da Bahia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Patients with post-COVID olfaction disorders for more than 3 months; aged between 18 and 65 years; with diagnostic documentation of COVID-19 through a positive test for SARS-CoV-2.
Exclusion Criteria
Traumatic brain injury; neurodegenerative and psychiatric illness; pregnancy; allergic rhinitis or other rhinosinusopathy; presence of smell disorder prior to COVID-19; use of topical or systemic corticosteroid therapy in the last 30 days; as well as current use of alpha-lipoic acid; omega 3; vitamin A; zinc or pentoxifylline will be excluded. Patients with a history of smell disorder less than 3 months and all those with previous treatment of the olfactory complaint will also be excluded.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Objective improvement in olfactory function of at least 1 point in the Connecticut olfactory test after 12 weeks of treatment.
- Secondary Outcome Measures
Name Time Method Subjective improvement of olfactory function through visual analogue scale assessment after 4, 8 and 12 weeks of treatment; olfactory function recovery time; correlation of collected clinical data with olfactory prognosis.