A randomised controlled trial of the effect of exercise training on exercise capacity in older patients with heart failure
Completed
- Conditions
- Chronic heart failureCirculatory System
- Registration Number
- ISRCTN51615566
- Lead Sponsor
- niversity of Dundee (UK)
- Brief Summary
2012 results in: http://www.ncbi.nlm.nih.gov/pubmed/22271753
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 112
Inclusion Criteria
Patients will be recruited from day hospital, heart failure and cardiology clinics
1. Patients aged 70 years or older
2. Diagnosis of chronic heart failure according to the European Society of Cardiology guidelines
3. Evidence of Left Ventricular (LV) systolic dysfunction
4. In the New York Heart Association class II or III
Exclusion Criteria
1. Aortic stenosis with peak gradient >30 mmHg
2. Sustained Ventricular Tachycardia (VT) or Ventricular Fibrillation (VF) outside of the context of an acute myocardial infarction
3. Unstable angina
4. Unable to walk without human assistance
5. Atrial fibrilation with a ventricular rate of >100/min
6. Currently enrolled in another trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in 6 minute walking distance, recorded at baseline, 8 and 24 weeks
- Secondary Outcome Measures
Name Time Method The following will be recorded at baseline, 8 and 24 weeks: <br>1. Change in quadriceps muscle strength<br>2. Repetitive strength<br>3. Incremental shuttle walk test<br>4. Quality of life<br>5. Carer strain<br>6. Mood and self reported function