Skip to main content
Clinical Trials/NCT01886417
NCT01886417
Completed
Not Applicable

Electromyography Study of Lip Muscles During Auditory Verbal Hallucinations Without Subvocalization in Patients With Schizophrenia

University Hospital, Grenoble1 site in 1 country40 target enrollmentOctober 2009
ConditionsSchizophrenia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Schizophrenia
Sponsor
University Hospital, Grenoble
Enrollment
40
Locations
1
Primary Endpoint
Labial EMG activity during auditory verbal hallucination
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

Auditory verbal hallucinations (AVHs) are speech perceptions in the absence of a relevant external stimulation. Some accounts of AVHs claim that a deficit in inner speech monitoring would cause the verbal thoughts of the patient to be perceived as external voices resulting in AVHs.

In order to examine whether AVHs correspond to self-generated inner speech, the present study aims at collecting speech muscle activity during covert AVHs (without articulation), overt speech and rest. Surface electromyography (sEMG) is used on schizophrenia patients and control subjects to detect any speech muscle activity during AVH.

Registry
clinicaltrials.gov
Start Date
October 2009
End Date
March 2015
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Grenoble
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Healthy controls:
  • must be more than 18 years and less than 60 years old
  • pre-inclusion medical examination
  • must have signed consent form
  • must be able to read stimuli on a screen
  • Schizophrenia patients:
  • must be more than 18 years and less than 60 years old
  • pre-inclusion medical examination
  • must have signed consent form
  • must be able to read stimuli on a screen

Exclusion Criteria

  • Healthy controls:
  • if aged less than 18 years or more than 60 years
  • diagnosed with any psychiatric disorder
  • with any language disorder (aphasia, SLI, dysarthria, stuttering, etc.)
  • with auditory impairment
  • pregnant, parturient, breast-feeding
  • Schizophrenia patients:
  • if aged less than 18 years or more than 60 years
  • significant secondary effects of antipsychotic medication, measured with the Barnes and AIMS scales
  • with a neurodegenerative disease

Outcomes

Primary Outcomes

Labial EMG activity during auditory verbal hallucination

Time Frame: up to 3 years

Study Sites (1)

Loading locations...

Similar Trials