Electromyography Study of Lip Muscles During Auditory Verbal Hallucinations Without Subvocalization in Patients With Schizophrenia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Schizophrenia
- Sponsor
- University Hospital, Grenoble
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Labial EMG activity during auditory verbal hallucination
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
Auditory verbal hallucinations (AVHs) are speech perceptions in the absence of a relevant external stimulation. Some accounts of AVHs claim that a deficit in inner speech monitoring would cause the verbal thoughts of the patient to be perceived as external voices resulting in AVHs.
In order to examine whether AVHs correspond to self-generated inner speech, the present study aims at collecting speech muscle activity during covert AVHs (without articulation), overt speech and rest. Surface electromyography (sEMG) is used on schizophrenia patients and control subjects to detect any speech muscle activity during AVH.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy controls:
- •must be more than 18 years and less than 60 years old
- •pre-inclusion medical examination
- •must have signed consent form
- •must be able to read stimuli on a screen
- •Schizophrenia patients:
- •must be more than 18 years and less than 60 years old
- •pre-inclusion medical examination
- •must have signed consent form
- •must be able to read stimuli on a screen
Exclusion Criteria
- •Healthy controls:
- •if aged less than 18 years or more than 60 years
- •diagnosed with any psychiatric disorder
- •with any language disorder (aphasia, SLI, dysarthria, stuttering, etc.)
- •with auditory impairment
- •pregnant, parturient, breast-feeding
- •Schizophrenia patients:
- •if aged less than 18 years or more than 60 years
- •significant secondary effects of antipsychotic medication, measured with the Barnes and AIMS scales
- •with a neurodegenerative disease
Outcomes
Primary Outcomes
Labial EMG activity during auditory verbal hallucination
Time Frame: up to 3 years