Hen's Egg Allergy Prevention Study

Not Applicable

• Conditions: hen's egg allergy; L20.9; J45.9; Other adverse food reactions, not elsewhere classified; Atopic dermatitis, unspecified; Asthma, unspecified; T78.1; T78.0; Anaphylactic shock due to adverse food reaction

• Registration Number: DRKS00005668
• Lead Sponsor: Charité Campus Virchow-Klinikum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 527

Inclusion Criteria

birth of baby of > 35 weeks gestational age, birth weight > 2,5 kg, sufficient knowledge of German language

Exclusion Criteria

birth of baby of < 35 weeks gestational age, birth weight < 2,5 kg

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitization to hen's egg protein at the age of 12 months will be determined through measurement of hen's egg-specific serum IgE (ImmunoCAP FEIA) at 12 months of age.

Secondary Outcome Measures

Name	Time	Method
IgE-mediated hen's egg allergy at the age of 1 year confirmed by double blind placebo controlled oral hen's egg challenge in all children with hen's egg-specific IgE levels >0.35 kU/l (see primary endpoint).