Correlation of C reactive protein with various Cardiovascular risk scores in patient with rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic systemic auto immune disease with a worldwide prevalence of approximately 0.5% to 1% among adults. In India prevalence of RA range 0.28 to 0.7% .Atherosclerosis is now recognised as an inflammatory disease, and the two diseases, atherosclerosis and RA, are considered to share many similarities . Patients with RA experience elevated risk of cardiovascular disease (CVD)including 50–70% higher risk of heart disease than the general population.Patient of RA often have elevated levels of circulating inflammatory markers such as C-reactive protein (CRP). CRP,Overall CVD risk in RA patient has two components. The first one is set of traditional risk factor for the general population. The interheart study has demonstrated the effect well- known factor associated with atherosclerosis.  The second component is a set of risk factors such as inflammatory mediator, treatment and disease activity in RA Patientswith RA have an increased risk of mortality and main cause is CV relatedevents. RA patient have chronic high grade inflammation which contribute towardsdevelopment premature atherosclerosis and CV events. The present study isundertaken to evaluate the CV risk using traditional CV risk algorithms (Framinghamrisk score, QRISK, INTERHEART risk score)for management of RA and to analyse associationof inflammatory marker to the traditional CV risk factors.