Azathioprine in Recurrent Implantation Failure

Phase 2

Completed

• Conditions: Recurrent Implantation Failure; In Vitro Fertilization; Intracytoplsmic Sperm Injection
• Interventions: Drug: Azathioprine Pill; Drug: Placebo Oral Tablet

• Registration Number: NCT03498703
• Lead Sponsor: Ain Shams University

Brief Summary

Azathioprine increase pregnancy rate in patients with recurrent implantation failure

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-04-07
• Study First Submitted QC: 2018-04-12
• Study First Posted: 2018-04-17
• Study Start: 2018-04-25
• Status Verified: 2019-07
• Primary Completion: 2019-07-01
• Study Completion: 2019-07-01
• Last Update Submitted: 2019-07-23
• Last Update Posted: 2019-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• age: 20-39
• previous 3 or more failed ivf

Exclusion Criteria

• intrauterine anomalies
• chronic systemic illness
• chronic pelvic conditions
• sensitivety to azathioprine

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Azathioprine	Azathioprine Pill	-
Control	Placebo Oral Tablet	-

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate	2 weeks

Secondary Outcome Measures

Name	Time	Method
Side effects	2 weeks

Trial Locations

Locations (2)

Ain Shams University, Maternity Hospital; 🇪🇬 Cairo, Egypt

Capital Birth Center; 🇪🇬 Cairo, Egypt