Comparing the Intra operative and Post operative effects Dexmedetomidine and Fentanyl used in total intravenous anaesthesia .

Not yet recruiting

• Conditions: Inflammatory disease of cervix uteri,

• Registration Number: CTRI/2019/03/017897
• Lead Sponsor: Dr Madhumitha Vijay

Brief Summary

A Randomised study to compare the efficacy of Propofol-Dexmedetomidine verusus Propofol-Fentanyl in terms of recovery time ,incidence of post operative nausea and vomiting, haemodynamic stability in patients undergoing minor gynaecological procedures.The most commonly used combination for day care anaesthesia is propofol with advantages in  of rapid recovery,being held as primary anaesthetic agent for the total intravenous (IV) anaesthesia combined with opioids.Opioids are well known to produce side effects like respiratory depression ,nausea and vomiting and affecting the early recovery,delaying both discharge and return of normalcy for the patient. Hence this study will be done to evaluate the efficacy of opioids and non opioid agent(Dexmedetomidine) in day care gynaecological procedures.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-02-28
• Study Start: 2019-04-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

1.Age group from 18 to 60 2.ASA 1.

Exclusion Criteria

• BMI < 18 to > 30 2.Patient with cardiac pathology 3.Known allergy to Propofol, Dexmedetomidine and Fentanyl.
• 4.Chronic hypertension 5.Patient with cardiac pathology 6.Chronic opioid treatment (Patient receiving sedation or analgesia).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Propofol-Dexmedetomidine versus Propofol-Fentanyl in terms of recovery time.	Intra operative and Post operative.

Secondary Outcome Measures

Name	Time	Method
To compare the time taken for eye opening after last dose of Propofol in both the groups.	To compare the incidence of post operative nausea and vomiting in both the groups.

Trial Locations

Locations (1)

Shri Sathya Sai medical college hospital and research institute; 🇮🇳 Kancheepuram, TAMIL NADU, India

Shri Sathya Sai medical college hospital and research institute

🇮🇳Kancheepuram, TAMIL NADU, India

Dr Madhumitha

Principal investigator

6374076336

madhuvijay195@gmail.com