A trial to assess the effectiveness of inhaled glycopyrrolate in improving the visual clarity during insertion of endotracheal tube with the help of fiberscope.
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/03/041048
- Lead Sponsor
- AIIMS PATNA
- Brief Summary
In this study, inhaled glycopyrrolate is used as a premedication inorder to reduce the airway secretions to improve the fibreoptic visual field during nasotracheal intubation.
According to DAS guidelines for awake tracheal intubation,use of systemic antisialogogue is not mandatory, however its also stated that fibrescopy view may be improved with antisialogogue.
Inhaled glycopyrrolate ,currently approved for management of COPD has not been evaluated for its anti secretory effect.Hence usage of inhaled glycopyrrolate is expected to have less systemic side effects and thus can be a better alternative to systemic antisialogogue.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 70
ASA physical status 1 and 2 of either sex undergoing elective surgery Age of 18 to 65 years Anticipated difficult airway in which fibreoptic intubation is planned under general anaesthesia.
Patients in which other modalities of intubation is planned Airway obstruction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate and compare the degree of airway secretion with or without use of inhaled glycopyrrolate prior to fibreoptic intubation Intraoperative at the time of fibreoptic intubation
- Secondary Outcome Measures
Name Time Method Time to reach carina The change in heart rate and blood pressure 20 min after nebulization
Trial Locations
- Locations (1)
AIIMS Patna
🇮🇳Patna, BIHAR, India
AIIMS Patna🇮🇳Patna, BIHAR, IndiaDr M N PradhanPrincipal investigator9008657262pradhanbangaloremn@gmail.com