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LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary Syndromes

Phase 3
Completed
Conditions
Acute Coronary Syndromes
Registration Number
NCT00214630
Lead Sponsor
AstraZeneca
Brief Summary

Comparison of rosuvastatin and atorvastatin in subjects with acute coronary syndromes

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
825
Inclusion Criteria
  • Non-ST segment elevation ACS and ST segment elevation ACS who receive optimal reperfusion therapy
Exclusion Criteria
  • Previous Q-wave infarct within the last 4 weeks
  • CK elevation not caused by myocardial injury
  • uncontrolled hypertension at time of randomization

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Reduction of LDL-C following 12 weeks of treatment
Secondary Outcome Measures
NameTimeMethod
% change from baseline in LDL-C following 2 & 6 weeks of treatment; % change from baseline in TC, HDL-C, triglycerides, non-HDL-C, apolipoprotein A-1, apolipoprotein B, LDL-C/HDL-C, TC/HDL-C, non-HDL-C/HDL-C, ApoB/Apo A-1 @ weeks 6 & 12

Trial Locations

Locations (1)

Research Site

🇵🇦

Panama City, Panama

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