Multi-parametric Magnetic Resonance Imaging for Prostate Cancer Patients
- Conditions
- Prostate Cancer
- Registration Number
- NCT03180398
- Lead Sponsor
- Henry Ford Health System
- Brief Summary
This is a pilot study of implement multi-parametric MR imaging for organ delineation and tumor response assessment of prostate cancer patients being treated with radiation therapy.
- Detailed Description
The study aims to generate intraprostatic lesions maps based on imaging, perform the treatment planning to compute the highest feasible simultaneous boosting dose to intraprostatic lesion and characterize longitudinal changes in imaging characteristics.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Male
- Target Recruitment
- 9
- Histologically confirmed prostate adenocarcinoma
- Patients with metal fragments or implanted devices such as pacemakers and aneurysm clips are not eligible for the study considering
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Detection of Imaging Biomarkers to Localize the Intraprostatic Lesions and Predict Radiation Treatment Response 2 years Identify the radiomics features selected from multimodal MRI to distinguish the dominant lesions from the normal tissues within the prostate. Track the changes of these features with longitudinal MRI scans to identify its correlation with the local control.
Tumor Response 2 years Tumor response as measured by an increase in PSA.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Henry Ford Health System
🇺🇸Detroit, Michigan, United States
Henry Ford Health System🇺🇸Detroit, Michigan, United States