eoadjuant chemoradiothrapy in treatment of proximal gastric cancer
Phase 2
Recruiting
- Conditions
- Gastric cancer.Stomach, unspecified
- Registration Number
- IRCT2017070834945N1
- Lead Sponsor
- Vice-chancellery for Research and Technology, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
performance status 0, 1 and 2; surgery in future treatment planning; and good condition for chemotherapy, radiotherapy and surgery.
Exclusion criteria: metastasis; death.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Resectability of tumor or R0 resection. Timepoint: After 15 weeks of neoadjuant therapy. Method of measurement: Pathology report after surgery.
- Secondary Outcome Measures
Name Time Method Myelosuppression. Timepoint: every 7 days during treatment. Method of measurement: complete blood count.;Nausea. Timepoint: On a weekly basis. Method of measurement: Based on the scale provided by Common Terminology Criteria for Adverse Events, Version 4.;Vomiting. Timepoint: On a weekly basis. Method of measurement: Based on the scale provided by Common Terminology Criteria for Adverse Events, Version 4.;Hair loss. Timepoint: On a weekly basis. Method of measurement: Based on the scale provided by Common Terminology Criteria for Adverse Events, Version 4.