Targeting microvascular impairment in patients with peripheral arterial disease: efficacy of lower limb revascularisation combined with supervised exercise therapy

niversity of the Sunshine Coast0 sites30 target enrollmentSeptember 5, 2016

Overview

No summary available.

Registry

who.int

Start Date

September 5, 2016

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of the Sunshine Coast

•1\. Patients scheduled for lower limb revascularisation, including open surgery (e.g. bypass), an endovascular procedure, or a hybrid procedure (e.g. endarterectomy plus angioplasty);
•2\. Documented diagnosis of PAD based on symptoms (claudication or critical limb ischaemia), an ABI \< 0\.90, and imaging evidence of a significant (\>50%) stenosis in at least one lower\-limb arterial segment;
•3\. Stable medication and treatment regimen (\>3 months);
•4\. Physician\-assessed ability to undertake the intervention and exercise testing.

•1\.Not able to walk independently prior to revascularisation, or walking capacity is limited by symptoms not related to PAD (including neuropathy);
•2\.Have had or are undergoing a significant amputation (e.g. forefoot, leg) that is expected to limit ability to walk independently after surgery;
•3\.Exercise testing is contraindicated for reasons such as unstable angina, uncontrolled hypertension (\>160/100\), limiting venous disease or uncontrolled cardiac dysrhythmias;
•4\.Current or planned involvement in a supervised exercise rehabilitation program.