NL-OMON44678
Completed
Not Applicable
Reducing Micro Vascular dysfunction In revascularized STEMI patients by off-target properties of ticagrelor - REDUCE-MVI
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 110
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Provision of informed consent
- •2\. Patients presenting with STEMI \<12 hours
- •3\. Successful PCI of the infarct\-related vessel with a modern DES
- •4\. Intermediate stenosis in non\-infarct\-related vessel (50\-90%)
Exclusion Criteria
- •1\. history of myocardial infarction
- •2\. Participation in another clinical study with an investigational product during the preceding 30 days
- •3\. history of cerebrovascular accident (CVA) or 'transient ischaemic attack' (TIA)
- •4\. History of intracranial haemorrhage
- •5\. indication or use of oral anticoagulant therapy (i.e. acenocoumarol)
- •6\. severe liver dysfunction (Child\-Pughscore 10\-15\)
- •7\. congestive heart failure
- •8\. cardiogenic shock
- •9\. left ventricular ejection fraction \< 35%
- •10\. bleeding diathesis
Outcomes
Primary Outcomes
Not specified
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