The Effect of mikrovascular decompression on microstructural changes in the affected nerve in patients with trigeminal neuralgia
Recruiting
- Conditions
- healthy subjectsG50.0Trigeminal neuralgia
- Registration Number
- DRKS00009870
- Lead Sponsor
- Klinik für Neurochirurgie, Uniklinik Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients with trigeminal neuralgia:
1.Patients has trigeminal neuralgia and a microvascular decompression has been scheduled
2.Signed consent
3.Patient is of full age
4.Missing exclusion criteria
Kontroll:
1. Medical indication for an MRI with the follwoing sequences: DTI, T1, T2 und ggf. CISS.
2. Signed consent
Exclusion Criteria
Trigeminus-Patienten:
1.Implants containing metal and or pace makers because of which an MRI is not possible.
Kontroll-Patienten:
1. Known cranial nerve deficit of any sort.
2. Meningitis / inflamatory CSF-syndrom (incl. Multiple Sklerosis).
3. Any intracranial maligne Process with proven cells in the CSF.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of FA-normalisation (DTI-MRI) with clinical recovery after MVD measured by a standardised BPI-facial questionaire after 3 months.<br>
- Secondary Outcome Measures
Name Time Method Evaluating the DTI-method as a possible predicitive instrument in patients with trigeminal neuralgia and the correlation with the intraoperative findings concerning neuro-vascular conflict.<br>