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Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization

Not Applicable
Conditions
Post-operative Pain
Interventions
Drug: Nano-propolis
Drug: saline
Drug: Propolis
Registration Number
NCT03591172
Lead Sponsor
Cairo University
Brief Summary

this study will assess different irrigating materials on the success revascularization of necrotic mature teeth associated with PRF.

Detailed Description

Nano-propolis and Propolis will be used as final endodontic irrigants and will be compared to saline in Revascularization of necrotic mature teeth.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
75
Inclusion Criteria
  • mature teeth.
  • teeth with periapical periodontitis.
  • Maxillary anterior teeth
  • Patients should be free from any systemic disease
  • Patients who will agree to the consent and will commit to follow-up period.
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Exclusion Criteria
  • Patients with immature roots.
  • Patients with any systemic disease that may affect normal healing.
  • Patients with swelling. .Pregnant females. .Patients who could/would not participate in a 1-year follow-up. .Patients with fistula. .Patients with old age. .Teeth with periodontal involvement. .Teeth with vertical root fractures. .Non-restorable teeth.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Nano-propolisNano-propolisnatural antibacterial, anti-inflammatory irrigation solution
salinesalinesodium chloride irrigation solution
propolisPropolisnatural antibacterial, anti-inflammatory irrigation solution
Primary Outcome Measures
NameTimeMethod
post-operative pain: Visual analogue scale1 year

post-operative pain evaluated using Visual analogue scale , 0 no pain, 10 severe pain.

Secondary Outcome Measures
NameTimeMethod
periapical healing1 year

evaluated radiographically

sensitivity1 year

electric pulp tester

survival1 year

clinical evaluation

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