Innovative endoscopy for label-free optical biopsies in surgery of colorectal liver metastases and hepatocellular carcinoma

• Conditions: C22; C78.7; Secondary malignant neoplasm of liver and intrahepatic bile duct; Malignant neoplasm of liver and intrahepatic bile ducts

• Registration Number: DRKS00022261
• Lead Sponsor: niversitätsklinikum Carl Gustav Carus Dresden an der Technischen Universität Dresden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-09
• Study Completion: 2021-11-20
• Results First Posted: 2023-03-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

Included are patients = 18 years of age, who receive a liver resection because of HCC or CRLM, and give their informed consent

Exclusion Criteria

speech problems or impaired mental state, lack of compliance

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of the project is the translation of innovative optical techniques into clinical application to increase surgical accuracy in oncological liver surgery. The project is aimed at the development of methods for the intraoperative detection of intrahepatic tumor cells using hepatocellular carcinomas or colorectal liver metastases as examples. The main focus is on the resection margins immediately after resection. Within the scope of this study, optical devices are developed and initially tested ex situ on liver tissue samples.

Secondary Outcome Measures

Name	Time	Method
not available