MR/PET in the Evaluation of Patients With Esophageal Cancer

National Taiwan University Hospital1 site in 1 country80 target enrollmentMay 2014

ConditionsEsophageal Cancer

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Esophageal Cancer
Sponsor: National Taiwan University Hospital
Enrollment: 80
Locations: 1
Primary Endpoint: The imaging biomarkers determined by MR-PET
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In this prospective study, we will recruit newly diagnosed esophageal cancer patients and perform MR/PET before and after chemoradiation therapy. In MR, new image sequences will be added to the conventional sequences, such as high resolution image, DWI, DCE, cine imaging.

Detailed Description

Total 80 patients will be recruited and followed after treatment complete for at least two years. We will compare the staging accuracy of MR/PET and PET/CT, and also analyze parameters that are predictive of disease recurrence and patient survival.

Registry

clinicaltrials.gov

Start Date

May 2014

End Date

April 2018

Last Updated

8 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

National Taiwan University Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•newly diagnosed esophageal cancer patient
•age older than 20 years

Exclusion Criteria

•For the safety reason, patients with the following conditions are contraindicated to enter magnetic resonance imaging (MRI) machine due to the high magnetic field, including: cardiac pacemaker, metallic artificial valve, intracranial and mediastinal vascular clips, cardiac defibrillator, nerve stimulator, implanted drug deliver system, metallic foreign body in the eye globe, cochlear implant, metallic fragments in the dangerous body part, Swan-Ganz catheter, and other metallic implants within 8 weeks: such as cardiac valve, stent, coil, filter, and clips.
•patient who will receive endoscopic local therapy alone
•unable to finish the standard surgical or radiation treatment
•history of surgery or radiotherapy to the mediastinum
•renal insufficiency, contraindication to MR imaging and contrast injection patient who have the severe allergic reaction the Gadollium contrast agent
•patient who have the claustrophobic symptoms are also not suitable for this MR examination
•pregnancy or lactating women