Quality of life in patients with nonalcoholic fatty liver disease

• Conditions: K76.0; Fatty (change of) liver, not elsewhere classified

• Registration Number: DRKS00017767
• Lead Sponsor: niversitätsklinikum Leipzig, Klinik für Gastroenterologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-30
• Study Completion: 2020-12-31
• Results First Posted: 2022-02-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 121

Inclusion Criteria

1) Age >18 years
2) Written informed consent
3) Clinical diagnosis of nonalcoholic fatty liver disease

Exclusion Criteria

1) Participation in a clinical trial for the treatment of NAFLD
2) Existence of additional liver disease other than NAFLD
3) Alcohol consumption >30 g / d in men or >20 g / d in women
4) Language barrier with limited knowledge of German
5) Presence of hepatocellular carcinoma
6) Organ transplant recipient
7) Pregnancy and breastfeeding
8) Liver cirrhosis Child B or Child C

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
How common are anxiety, depression and pruritus in non-selected NAFLD patients?

Secondary Outcome Measures

Name	Time	Method
What is the overall quality of life in non-selected NAFLD patients?<br><br>What are the interactions between anxiety, depression and pruritus and general quality of life?<br><br>Do anxiety, depression and pruritus correlate with clinical parameters (e.g. the extent of sonographically measured liver stiffness (transient elastography, fibroscan®) as a surrogate parameter of hepatic fibrosis)?