11C-Methionin (MET) PET vs 18F-FDG PET in the follow-up of differentiated thyroid cancer.
Recruiting
- Conditions
- patients with negative post treatment 131I-whole body scan and elevated serum thyroglobulin and patients with persistent or recurrent Hürthlecell carcinoma in the post-ablation phase and during folluw-up.
- Registration Number
- NL-OMON24584
- Lead Sponsor
- no sponsor
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
Objective (study) 1:
1. > 18 years old;
Exclusion Criteria
Both objectives/studies:
1. Pregnancy;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A qualitative and semi-quantitative (standardized uptake values (SUVs)) reading of all the PET studies will be performed. Comparison with data derived from clinical CT imaging data, and where feasible histological or cytological confirmation, will take place.<br><br /><br /><br>Objective/Study 1: <br />The results of 11C-MET PET will be compared with the clinical FDG PET.<br /> <br>Objective/Study 2: <br />The results of 11C-MET PET will be compared with the clinical FDG PET.<br /> <br>The results of both PET scan will also be compared with the (diagnostic and) post-treatment 131I-WBS.<br>
- Secondary Outcome Measures
Name Time Method o secondary outcomes.