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Clinical Trials/NCT05115773
NCT05115773
Completed
N/A

Comparison of The Effectiveness of Intraligamentary and Mandibular Anesthesia on Mandibular Molar Teeth: A Randomized Clinical Study

Izmir Katip Celebi University1 site in 1 country78 target enrollmentFebruary 25, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Anesthesia, Local
Sponsor
Izmir Katip Celebi University
Enrollment
78
Locations
1
Primary Endpoint
Measurement of the injection pain of the local anesthesia using Wong Baker FACES pain rating scale.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study aimed to compare the effects of mandibular and intraligamentary anesthesia techniques on pain scores during restorative treatment of permanent mandibular molars in pediatric patients. Additionally, comparing the anesthesia techniques in terms of injection pain, the success of anesthesia, postoperative complications, and the subjects' preference was planned.

This randomized, controlled, cross-over, single-blind, split-mouth study was conducted on 78 subjects aged 6 to 12 years. Subjects with enamel-dentin caries on the bilateral permanent mandibular molar were included.

Detailed Description

First, the subjects who met the inclusion criteria in the study were included in 2 study groups according to age, gender, dental experience, DMFT / dmft values, and ICDAS II and radiographic evaluation criteria. Two different anesthesia techniques were applied to the right / left permanent first molar teeth of the patients included in the study, with an interval of one week. The subjects have been divided into two groups as 39 subjects were Group 1 received intraligamentary anesthesia in the first visit, and 39 subjects were Group 2 received mandibular anesthesia in the first session. The pain perception rates of the patients during the injection and treatment phases were recorded subjectively using a visual analog scale and Wong-Baker FACES pain rating scale. Heart rate and arterial oxygen saturation were determined as the physiological parameters. The quality of anesthesia and success were evaluated by the operation at the end of each visit. Complications (pain, raised teeth, hematoma, trauma due to lip/tongue bites, swelling, infection, and bleeding) were explained to the patients after anesthesia. They were asked to take note of the complications they encountered. Postoperative complications were recorded by calling the cases 1 day after the 1st and 2nd visits. At the end of the second visit, anesthesia preference of the patient was asked and recorded.

Registry
clinicaltrials.gov
Start Date
February 25, 2020
End Date
August 31, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Izmir Katip Celebi University
Responsible Party
Principal Investigator
Principal Investigator

Funda Cagırır Dindaroglu

Asst. Prof.

Izmir Katip Celebi University

Eligibility Criteria

Inclusion Criteria

  • Subjects with American Society of Anesthesiologists score I (ASA I)
  • Subjects with Frankl's behavior rate III (positive) and IV (definitely positive),
  • Subjects with indication of similar restoration treatment on bilateral first permanent mandibular molars
  • Subjects whose plaque index score of 0 (no plaque) and 1
  • Subjects whose gingival index score of 0

Exclusion Criteria

  • Allergic to the local anesthetics or sulfites
  • Subjects with cholinesterase deficiency
  • Subjects who use drugs that may affect the assessment of pain, such as narcotic or non-narcotic analgesic, anti-inflammatory, anxiolytic, antipsychotic and antihistamine agents
  • Subjects who need to use sedatives or other medications during dental procedures

Outcomes

Primary Outcomes

Measurement of the injection pain of the local anesthesia using Wong Baker FACES pain rating scale.

Time Frame: Immediately after the local anaesthetic injection

Subjective pain perception scores using Wong Baker Faces pain rating scale (Face 0: it does not hurt/best, Face 2: it hurts a little, Face 4: it hurts a little more, Face 6: it hurts more, Face 8: it hurts a lot, Face 10: it hurts a lot/worst)

The measurements of dental pain using Visual Analogue Scale

Time Frame: Immediately after the working with a low-speed rotary instrument on dentin

Subjective pain perception scores during the intervention using Visual Analogue Scale containing Numeric Rating Scale (0-10, where 0 means no pain/best, 10 - worst possible pain)

Practitioner's assessment of patient pain-related comfort

Time Frame: Immediately after the dental treatment

Practitioner's subjective records: cases who need additional mandibular anaesthesia, whose treatment is completed without a discomfort related to pain, who has a slight discomfort even though additional mandibular anaesthesia is not needed during the treatment

Change from baseline physiological parameters (arterial oxygen saturation and pulse rate) at the end of the working with a low-speed rotary instrument on dentin

Time Frame: Baseline and immediately after the local anaesthetic injection

Measurement of arterial oxygen saturation and pulse rate using a pulse oximeter

The measurements of injection pain using Visual Analogue Scale

Time Frame: Immediately after the local anaesthetic injection

Subjective pain perception scores after the local anesthetic injection using Visual Analogue Scale containing Numeric Rating Scale (0-10, where 0 means no pain/best, 10 - worst possible pain)

Measurement of the pain perception during the dental procedures using Wong Baker FACES pain rating scale.

Time Frame: Immediately after the working with a low-speed rotary instrument on dentin

Subjective pain perception scores using Wong Baker Faces pain rating scale (Face 0: it does not hurt/best, Face 2: it hurts a little, Face 4: it hurts a little more, Face 6: it hurts more, Face 8: it hurts a lot, Face 10: it hurts a lot/worst)

Rate of post-op complication

Time Frame: Day after intervention

Query the presence of post-op complications related to local anaesthesia

Secondary Outcomes

  • Evaluate the correlation between two self reported objective pain scales(Immediately after the local anaesthetic injection)

Study Sites (1)

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