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Identification of predictors associated with persisting PAIN in patients with rheumatoid Arthritis (RA) and CONTROLled disease activity

Conditions
Rheumatoid Arthritis
Registration Number
DRKS00010717
Lead Sponsor
AbbVie Deutschland GmbH Co. KG
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
647
Inclusion Criteria

- Adult patients with a confirmed diagnosis of rheumatoid arthritis according to American College of Rheumatology (ACR) 2010 criteria with active disease (DAS28 = 3.2) plus SJC > 3, CRP above the upper limit of normal or normal CRP value and planned initiation or escalation of anti-inflammatory Treatment
- Disease duration (RA) = 8 years
- Severe Pain (VAS (0-100) = 50))
- Patients with the intellectual capacity to take part in this study
- Adult patients whose signed written informed consent has been obtained

Exclusion Criteria

- Patients with a history of chronically manifested pain due to degenerative joint disease, previous surgery, myofascial or ligament dysfunction preceding the flare (active disease inclusion criterion)
- Patients with Fibromyalgia syndrome
- Patients with diabetic neuropathy
- Patients with Psoriasis

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Proportion of patients with severe, persisting pain Visual analogue scale(VAS (0-100) = 50) after week 12 and week 24 despite Disease Activity Score 28 (DAS28) response
Secondary Outcome Measures
NameTimeMethod
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