Investigating the effect of topical diltiazem and botulinum toxin injection in the treatment of chronic anal fissure

Phase 2

Recruiting

• Conditions: Chronic anal fissure.; Chronic anal fissure; K60.1

• Registration Number: IRCT20230607058408N1
• Lead Sponsor: Gonabad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

People with chronic anal fissure between the ages of 18 and 80

Exclusion Criteria

Immune deficiency (using corticosteroids for more than 3 months, patients receiving transplants, receiving chemotherapy or radiotherapy, HIV positive patients with CD4 less than 200)
Inflammatory bowel diseases
Tuberculosis
Recurrent anal fissure and complicated anal fissure (stenosis, abscess, fistula or hemorrhoids)
Colon malignancy
Pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chronic anal fissure. Timepoint: Examination of anal fissure at the beginning of the study and 14 days later and at the end of the first, second, fourth and sixth months after the intervention. Method of measurement: Checklist and questionnaire.