To compare the safety parameters of two different modes of a corneal strengthening procedure in patients with Keratoconus.
Not Applicable
Completed
- Conditions
- Health Condition 1: H186- Keratoconus
- Registration Number
- CTRI/2020/06/026093
- Lead Sponsor
- ethradhama Superspeciality Eye Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 44
Inclusion Criteria
1.Patients giving written informed consent.
2.Patients within age group of 10-40yrs.
3.Patients with progressive keratoconus.
4.Patients with pre-operative corneal thickness measured with pachymetry of more than 400microns.
Exclusion Criteria
1.corneal pachymetry less than 400 microns
2.decompensated cornea
3.corneal dystrophies
4.age > 40years and <10 years
5.pre-existing scar
6.severe dry eye
7.eyes with limbal stem cell deficiency.
8.corneal ectasia other thankeratoconus.
9.active ocular surface disorder.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy and safety of continuous and pulsed mode of corneal collagen cross linking for keratoconus patients.Timepoint: Relevant data will be collected preoperatively , at 1, 3, 6 months postoperatively.
- Secondary Outcome Measures
Name Time Method 1. Pre operative and post operative Uncorrected and best corrected visual acuity <br/ ><br>2. Pre operative and post operative changes in corneal parameters <br/ ><br>3. Pre operative and post operative changes in corneal thickness. <br/ ><br>4. To assess the depth of stromal demarcation line following treatment <br/ ><br>Timepoint: Relevant data will be collected preoperatively , at 1, 3, 6 months postoperatively.