Determing the cellular immunophenotype-genotype interactions in pancreatic cancer towards targeted personalized immunotherapies

Recruiting

• Conditions: pancreatic cancer; Pancreatic Ductal AdenoCarcinoma; 10017990

• Registration Number: NL-OMON45339
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Pancreatic cancer tissues and immune cells from patients diagnosed with severl types of pancreatic caner planned to undergo explorative surgery with or without resection.

Exclusion Criteria

Severe anemia (Hb<6.0 mmol/L)
Tumors <1 cm

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint consists in determining which immunophenotype-genotype<br /><br>interactions play a dominant role in the pathogenesis of PDAC and if we can<br /><br>therapeutically target these interactions. We will also be able to correlate<br /><br>the immunophenotyping with overall survival thereby conceptualizing an<br /><br>immunoprofile score.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>