Evaluating the contractile effect of two medicines, namely carbetocin and oxytocin, on the uterus, in patients undergoing cesarean surgery
Phase 3
- Conditions
- Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium
- Registration Number
- CTRI/2023/08/056162
- Lead Sponsor
- Amrita institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Parturient between 18 â?? 40 years undergoing elective caesarean section.
Exclusion Criteria
H/o significant Cardiac, renal or liver diseases.
Hypertensive disorder of pregnancy.
Multiple pregnancy.
Abnormal placenta.
Polyhydramnios.
Fibroid complicating pregnancy.
Epilepsy.
General anaesthesia.
Hypersensitivity to study medications and their preservatives
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the uterine tone with prophylactic intravenous oxytocin vs. carbetocin in parturients undergoing elective cesarean section under spinal anesthesia. <br/ ><br>Timepoint: 3 minutes <br/ ><br>
- Secondary Outcome Measures
Name Time Method Hemodynamic effects including heart rate, systolic blood pressure & mean arterial pressure after administration of the drug. <br/ ><br>Requirement of further uterotonic agents. <br/ ><br>Adverse effects. <br/ ><br>Timepoint: Till 15 minutes after delivery of baby