CO2 reactivity in the acute stage of aneurysmal subarachnoid hemorrhage.

• Conditions: hemorrhage between the brain membranes; subarachnoid hemorrhage; 10007963

• Registration Number: NL-OMON37010
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Aneurysmal subarachnoid hemorrhage
Inclusion within 3 days after the hemorrhage
Aged 18 years or older
Informed consent obtained

Exclusion Criteria

•Impaired renal function (Creatinine > 200 µmol/l)
•Diabetes Mellitus
•Acute general reactions to or contra-indications for the admission contrast CT-scan
•Pregnancy

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Occurrence of delayed cerebral ischemia, defined by a persisting clinical<br /><br>deterioration (i.e. new focal deficit, decrease in consciousness, or both) with<br /><br>no evidence for rebleeding or hydrocephalus on CT and no other medical causes,<br /><br>such as infections or metabolic disturbances, and with or without hypodensity<br /><br>on CT.<br /><br><br /><br>2. Occurrence of a disturbed CO2R test </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Occurrence of radiographic vasospasm and perfusion parameters on CT-P</p><br>