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Clinical Trials/NCT03920020
NCT03920020
Completed
Not Applicable

Comparison of The Effects of Concentric and Eccentric Isokinetic Exercises on Proprioception and Muscle Architecture in Patients With Knee Osteoarthritis

Hacettepe University1 site in 1 country43 target enrollmentJanuary 28, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
Hacettepe University
Enrollment
43
Locations
1
Primary Endpoint
Joint position sense
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in 42 patients with knee osteoarthritis enrolled the study.

Detailed Description

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in patients with knee osteoarthritis. 42 patients will be included in this study. Patients will be divided into three groups; concentric exercise group (n:14), eccentric exercise group (n:14) and control group (n:14). A conventional physiotherapy program and a standard therapeutic exercise program will be applied to all subjects. In addition to these exercise and physiotherapy programme, concentric and eccentric exercise groups will perform the exercises related to their groups. All three groups will participate in this program for a total of 18 sessions 3 times a week for 6 weeks. All groups will be subject to re-evaluation after 6 weeks.

Registry
clinicaltrials.gov
Start Date
January 28, 2019
End Date
December 31, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Aysun Baki

principal investigator

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of primary knee osteoarthritis according to American College of Radiology
  • Being radiographically K-L grade 2-3
  • Presence of symptoms for at least 3 months
  • Patients who have been planned a conventional physiotherapy programme because of knee osteoarthritis
  • Presence of functional capacity for outpatient physical therapy

Exclusion Criteria

  • Patients with seconder knee osteoarthritis
  • History of lower extremity or spine surgery
  • History of intraarticular injection in last 1 month
  • Patients with neurological disease that will affect muscle strength, balance and coordination

Outcomes

Primary Outcomes

Joint position sense

Time Frame: 6 weeks

Joint position sense will be evaluated with isokinetic dynamometer at predetermined angles.

Ultrasonographic assessment of quadriceps and hamstring muscles

Time Frame: 6 weeks

Ultrasonographic evaluation is an outcome measure to evaluate muscle structure. In our study ultrasonographic evaluation will be performed to determine the muscle structure (muscle thickness(mm), fascicle length(mm), pennation angle(degree)) of quadriceps and hamstring muscles. Muscle thickness will be defined as the distance between the deeper and upper aponeurosis. The pennation angle will be calculated as the angle of insertion of muscle fascicles into the deep aponeurosis. Fascicle length will be defined as the length of the fascicular path between the superficial and deep aponeurosis.

Secondary Outcomes

  • Muscle strength assessment(6 weeks)
  • Pain assessment: VAS (Visual analog scale)(6 weeks)
  • Balance assessment(6 weeks)
  • The timed up and go test(6 weeks)
  • Short Form 12 (SF-12) health survey(6 weeks)
  • WOMAC (Western Ontario & McMaster Universities Osteoarthritis Index)(6 weeks)
  • Range of motion(6 weeks)
  • Shortness of muscles assessment(6 weeks)
  • Sit to stand test(6 weeks)
  • Timed 10 meter walk test(6 weeks)

Study Sites (1)

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