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Comparison of The Effects of Concentric And Eccentric Isokinetic Exercises in Patients With Knee Osteoarthritis

Not Applicable
Completed
Conditions
Knee Osteoarthritis
Interventions
Other: the concentric isokinetic exercise group
Other: the eccentric isokinetic exercise group
Other: the control group
Registration Number
NCT03920020
Lead Sponsor
Hacettepe University
Brief Summary

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in 42 patients with knee osteoarthritis enrolled the study.

Detailed Description

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in patients with knee osteoarthritis. 42 patients will be included in this study. Patients will be divided into three groups; concentric exercise group (n:14), eccentric exercise group (n:14) and control group (n:14). A conventional physiotherapy program and a standard therapeutic exercise program will be applied to all subjects. In addition to these exercise and physiotherapy programme, concentric and eccentric exercise groups will perform the exercises related to their groups. All three groups will participate in this program for a total of 18 sessions 3 times a week for 6 weeks. All groups will be subject to re-evaluation after 6 weeks.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
43
Inclusion Criteria
  • Diagnosis of primary knee osteoarthritis according to American College of Radiology
  • Being radiographically K-L grade 2-3
  • Presence of symptoms for at least 3 months
  • Patients who have been planned a conventional physiotherapy programme because of knee osteoarthritis
  • Presence of functional capacity for outpatient physical therapy
Exclusion Criteria
  • Patients with seconder knee osteoarthritis
  • History of lower extremity or spine surgery
  • History of intraarticular injection in last 1 month
  • Patients with neurological disease that will affect muscle strength, balance and coordination

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
the concentric isokinetic exercise groupthe concentric isokinetic exercise groupthe concentric isokinetic exercise group will perform quadriceps and hamstring concentric isokinetic exercises in addition to the conventional physiotherapy and exercise program 3 times a week during 6 weeks.
the eccentric isokinetic exercise groupthe eccentric isokinetic exercise groupthe eccentric isokinetic exercise group will perform quadriceps and hamstring eccentric isokinetic exercises in addition to the conventional physiotherapy and exercise program 3 times a week during 6 weeks.
the concentric isokinetic exercise groupthe control groupthe concentric isokinetic exercise group will perform quadriceps and hamstring concentric isokinetic exercises in addition to the conventional physiotherapy and exercise program 3 times a week during 6 weeks.
the control groupthe control groupthe control group will perform the standard exercise program predetermined by us consisting of stretching exercises and isometric strengthening (these exercises will be done at home, too) and the conventional physiotherapy program will be applied 3 times a week during 6 weeks.
the eccentric isokinetic exercise groupthe control groupthe eccentric isokinetic exercise group will perform quadriceps and hamstring eccentric isokinetic exercises in addition to the conventional physiotherapy and exercise program 3 times a week during 6 weeks.
Primary Outcome Measures
NameTimeMethod
Joint position sense6 weeks

Joint position sense will be evaluated with isokinetic dynamometer at predetermined angles.

Ultrasonographic assessment of quadriceps and hamstring muscles6 weeks

Ultrasonographic evaluation is an outcome measure to evaluate muscle structure. In our study ultrasonographic evaluation will be performed to determine the muscle structure (muscle thickness(mm), fascicle length(mm), pennation angle(degree)) of quadriceps and hamstring muscles. Muscle thickness will be defined as the distance between the deeper and upper aponeurosis. The pennation angle will be calculated as the angle of insertion of muscle fascicles into the deep aponeurosis. Fascicle length will be defined as the length of the fascicular path between the superficial and deep aponeurosis.

Secondary Outcome Measures
NameTimeMethod
Muscle strength assessment6 weeks

isokinetic dynamometer test will be used.

Pain assessment: VAS (Visual analog scale)6 weeks

VAS is used to measure the psycometric pain severity in some conditions and activities. A VAS is usually a 100 mm long horizontal line. The scale is most commonly anchored by "no pain" (line's left, score-0), "pain as bad as it could be" (line's right, score-100). the score is determined by measuring the distance between the "no pain" anchor and the patient's mark.

Balance assessment6 weeks

Single leg standing test with eyes open and closed will be used. Timing is recorded.

The timed up and go test6 weeks

TUG test is used to measure functional mobility. It gives an idea about patients walking ability, fall risk and balance. The patient is asked to get up, walk 3 meters and sit down again.Timing begins when the patient rise from the chair and stops when the patient sit down.

Short Form 12 (SF-12) health survey6 weeks

SF-12 is an 12- item questionnare for assessing self-reported health related quality of life. It covers eight domains of health outcomes, including physical functioning, role physical, bodily pain, general health, vitality, social functioning,role-emotional, mental health. Sf-12 physical and mental component summary scales are scored. Lower SF-12 score indicated poorer physical and mental health.

WOMAC (Western Ontario & McMaster Universities Osteoarthritis Index)6 weeks

WOMAC Osteoarthritis Index (score range 0-100) include 3 subscales and will be used to evaluate knee pain(score range 0-20), stiffness (score range 0-8), and functional limitation (score range -68). Womac is comprised of 24 items ( pain-5 items, stiffness-2 items, physical function-17 items). All items are scored on a scale of 0-4. Lower scores indicate lower disability.

Range of motion6 weeks

Universal goniometer will be used for assessment of range of motion of the knee

Shortness of muscles assessment6 weeks

universal goniometer will be used for assessment

Sit to stand test6 weeks

Patients stand up from and sit down on a chair as quickly as possible 5 times. Patients folded their arms across their chests. Timing is recorded.

Timed 10 meter walk test6 weeks

This test is used to assess walking speed. Timing is recorded.

Trial Locations

Locations (1)

Institute of Health Sciences

🇹🇷

Ankara, Altındağ, Turkey

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